Dutasteride Mesotherapy for Androgenetic Alopecia

Androgenetic alopecia (AGA), commonly known as male or female pattern hair loss, is a prevalent condition affecting many individuals worldwide. It is primarily driven by dihydrotestosterone (DHT), a hormone that contributes to the miniaturization of hair follicles, leading to progressive hair thinning and loss. Traditional treatments have included oral medications and topical applications. However, recent advancements have introduced mesotherapy with dutasteride as a promising alternative.

Understanding Dutasteride Mesotherapy

Dutasteride is a potent inhibitor of the 5-alpha-reductase enzyme, which is responsible for converting testosterone into DHT. By inhibiting this conversion, dutasteride effectively reduces DHT levels, thereby addressing one of the root causes of AGA. Mesotherapy involves the intradermal injection of micro-doses of dutasteride directly into the scalp, targeting affected hair follicles. This localized delivery aims to maximize therapeutic effects while minimizing systemic exposure and potential side effects.

Clinical Outcomes and Benefits

Several studies have explored the efficacy of dutasteride mesotherapy in treating AGA:

• Efficacy in Hair Density Improvement: A retrospective study involving 541 patients reported that over 80% experienced clinical improvement after receiving 0.01% dutasteride mesotherapy injections every three months. Notably, 38.4% of these patients observed marked improvement in hair density.

• Comparison with Oral Administration: Research indicates that both oral and mesotherapy administrations of dutasteride are effective. However, mesotherapy presents a favorable safety profile with fewer systemic side effects. 

Safety and Potential Adverse Effects

Dutasteride mesotherapy is generally well-tolerated. The most commonly reported side effect is localized pain at the injection site.. Importantly, studies have not detected serious or systemic adverse events, including sexual dysfunction, which are sometimes associated with oral 5-alpha-reductase inhibitors.

Frequently Asked Questions (FAQ)

• What is dutasteride mesotherapy?

  • It is a treatment for androgenetic alopecia involving the injection of dutasteride directly into the scalp to inhibit DHT production and promote hair regrowth.

• How does it differ from oral dutasteride treatment?

  • Mesotherapy delivers the medication directly to the affected area, potentially reducing systemic side effects associated with oral administration.

• What can I expect during the procedure?

  • The procedure involves multiple small injections into the scalp. Some patients report mild discomfort or pain at the injection sites.

• How many sessions are required to see results?

  • Treatment protocols vary, but sessions are often conducted every 3 months. Clinical improvements have been observed after multiple sessions

• Are there any side effects?

  • The most common side effect is localized pain during injection. Serious systemic side effects are rare.

• Is dutasteride mesotherapy suitable for everyone?

  • While many individuals with AGA may benefit, it's essential to consult with a healthcare provider to determine if this treatment is appropriate for you.

• Who is an expert at Hairloss and using Mesotherapy?

  • Dr. Matthew Sandre, a Board-Certified Dermatologist, is a nationally recognized expert in androgenic alopecia. Explore his journal article on mesotherapy here: https://canadiandermatologytoday.com/article/view/5-2-sandre/pdf_en

At Unify Health, we are committed to offering advanced and personalized treatments for hair loss. Our team of experienced professionals will work with you to develop a tailored plan that addresses your specific needs and goals.

PLATELET RICH PLASMA (PRP) FOR HAIRLOSS

We proudly offer Platelet-Rich Plasma (PRP) treatment for hair loss provided by our board-certified Dermatologists. PRP is a cutting-edge, non-surgical treatment that uses your own blood plasma to promote hair growth and reverse hair loss. This innovative treatment has been extensively researched and is a safe and effective solution for those suffering from hair loss.

At Unify, our Dermatologists are highly trained and experienced in PRP treatment for hair loss. They use the latest techniques and equipment to ensure that every patient receives the highest quality of care. During the PRP treatment, a small sample of the patient's blood is drawn and processed to concentrate the platelets. This concentrated plasma is then injected into the scalp, providing the necessary growth factors to promote hair growth and reverse hair loss.

Numerous scientific studies have shown the effectiveness of PRP for hair loss. A meta-analysis published in the Journal of Clinical and Aesthetic Dermatology in 2018 found that PRP treatment led to significant improvements in hair density, thickness, and overall hair growth (1). In another recent meta-analysis, PRP was more effective than Minoxidil (Rogaine) in treating male pattern hair loss with an increased benefit when using both treatments (2). Additionally, a randomized controlled trial published in the Journal of Dermatological Treatment in 2020 found that PRP was more effective than placebo in promoting hair growth and reducing hair loss (3).

At Unify, we understand the impact that hair loss can have on one's confidence and self-esteem. We are dedicated to providing our patients with the best care and treatment options. Our team of expert Dermatologists will work with you to determine if PRP is the right solution for your hair loss and will guide you through every step of the process. Typically our Dermatologists recommend 3-5 treatments before evaluating efficacy and suggesting further treatment.

PRP for Hair Loss - Frequently Asked Questions (FAQ)

• What is PRP therapy for hair loss?

  • Platelet-Rich Plasma (PRP) therapy is a non-surgical treatment that uses your own blood to promote hair growth. The process involves drawing a small amount of blood, processing it to concentrate the platelets, and injecting the PRP into areas of the scalp experiencing hair thinning or loss. PRP contains growth factors that stimulate hair follicles, encouraging natural hair regrowth.

• Who is a good candidate for PRP therapy?

  • PRP is ideal for individuals experiencing early to moderate hair thinning, particularly those with androgenetic alopecia (male and female pattern baldness). It is most effective for those who still have active hair follicles. It may not be suitable for individuals with complete baldness, certain medical conditions, or those on specific medications.

• How many treatments are required?

  • Atypical PRP treatment plan involves an initial series of three to four sessions spaced 4 to 6 weeks apart, followed by maintenance treatments every 4 to 6 months for optimal results. The exact number of treatments may vary based on individual response and goals.

• When will I see results?

  • Most patients start noticing improvements in hair thickness and reduced shedding within three to six months after starting treatment. Continued improvement occurs over time with regular maintenance.

• Is PRP Therapy Painful?

  • Most patients tolerate the procedure well. The injections may cause mild discomfort, but a topical numbing cream can be applied beforehand to minimize any pain. We also offer Penthrox analgesia for $250 extra per treatment. Some patients report mild soreness or swelling in the treated area, which typically subsides within a day or two.

• Are there any side effects?

  • PRP therapy is a safe procedure since it uses your own blood, reducing the risk of allergic reactions or infections. Some patients may experience mild redness, swelling, or tenderness at the injection site, which typically resolves within a few days.

• Can PRP be combined with other hair loss treatments?

  • Yes, PRP therapy can be used in combination with other hair restoration treatments such as topical minoxidil (Rogaine), oral finasteride (Propecia), low-level laser therapy (LLLT), and hair transplant procedures for enhanced results. A consultation with our specialists will determine the best approach for your needs.

• How long do the results last?

  • Results vary by individual, but with regular maintenance treatments, most patients experience long-lasting improvement in hair density and quality. Without maintenance, hair thinning may gradually resume over time.

• Is PRP covered by insurance?

  • PRP for hair loss is considered a cosmetic procedure and is not covered by OHIP or most private insurance plans.Hair loss consult: $150.00 and is put towards your PRP or mesotherapy if you choose to do this. Treatments are $750.00 per treatment

• How do I book a consultation?

  • To schedule a consultation for PRP therapy, please call 416-745-1555 or at at info@unifyhealth.ca. Our team will assess your hair loss concerns and develop a personalized treatment plan tailored to your needs.